Initially, such lesions were encountered in the orthopedic field, but Jerry Bouquot and other researchers found these lesions in the jaw bones in their examinations of patients who presented with facial pain of unknown cause. Below you can see what a healthy bone looks like and unhealthy bone tissue taken from the jawbone after the death of a patient with a NICO.
NICO – Cavitations
Although NICO means neuralgia, that is, dead areas in the jawbone that cause nerve-induced pain, in some patients it can creep in the bone without any symptoms.
Researchers such as J. Lechner have detected very high amounts of RANTES / RANKL inflammatory elements in these lesions. What are these elements? In other fields of medicine, these agents have been found to be elevated in the blood or cerebrospinal fluid in many conditions such as MS, ALS, rheumatoid arthritis, chronic fatigue syndrome, breast cancer, and trauma. The amount of RANTES measured in the jawbone can even exceed these levels. Therefore, such lesions are thought to have a role in inflammatory diseases.
Currently, the most known treatment method recommended for this condition is to reach these areas surgically, curettage and allow the bone to heal again. In order for the bone metabolism to function well, it is as important as before and after the operation. The patient is prepared for the operation with diet, lifestyle changes and supplements that will help bone healing to be healthy. In addition, supporting healing with methods such as ozone and PRF can increase the chance of success.